Cedars-Sinai Health Sciences University researchers have found a new way to use MRIs to accurately measure myocardial oxygen consumption.
The study, published March 25 in Science Translational Medicine, said researchers placed patients into an MRI to take multiple scans over the course of several minutes, while drawing blood at the same time. Researchers demonstrated the accuracy of the MRI method to measure the heart’s oxygen consumption by using it on patients with and without heart failure and comparing the results to readings obtained from a heart catheterization.
“Our study shows how MRI could be used to quickly and noninvasively determine heart oxygen use in the clinic,” corresponding study author Hsin-Jung Yang, PhD, director of cardiac imaging research in the Biomedical Research Imaging Institute, said in a March 25 system news release. “The system we designed addresses the motion of the heart. Patients do not need to hold their breath, and it can give precise numbers within three minutes. With further research and development, this advance could unlock new frontiers in early diagnosis, personalized therapy and next-generation treatments for heart failure.”
Poor oxygen use by the heart is an early indicator of heart failure. The current gold standard to measure oxygen use is coronary sinus catheterization. This procedure takes 30 to 60 minutes and involves injection of contrast dye to guide the catheter. However, it is too invasive for routine heart oxygen monitoring.
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