GLP-1s and heart outcomes: 5 recent findings

With deaths from obesity-related heart disease reportedly increasing by 180% over the past 20 years, more research is being done to learn how GLP-1 medications such as Ozempic, Wegovy, Mounjaro and Zepbound can address outcomes in cardiovascular health. 

Advertisement

Here are five recent research findings:

  1. Among patients with Type 2 diabetes, GLP-1 medications reduced major adverse cardiovascular events by 13% when compared to a placebo.
  2. Tirzepatide, the active ingredient in Eli Lilly’s GLP-1 medications Mounjaro and Zepbound, reduced the risk of heart failure by 46% and the risk of both heart failure or cardiovascular death by 38% among individuals with obesity.
  3. Stroke survivors who took GLP-1 or SGLT2 medications had a 74% lower risk of death and an 84% lower risk of heart attack compared to patients who did not take either medication.
  4. The death rate among stroke survivors who took either a GLP-1 or an SGLT2 was 11.8% and the heart attack rate was 1.5%, compared to 54% and 6.1%, respectively, for patients who did not take either medication.
  5. Semaglutide, the active ingredient in Novo Nordisk’s GLP-1 medications Ozempic and Wegovy, reduced annual healthcare costs by $7,502 for patients with overweight or obesity, and by $9,276 for patients with heart failure or atherosclerotic cardiovascular disease.

At the Becker's 23rd Annual Spine, Orthopedic and Pain Management-Driven ASC + The Future of Spine Conference, taking place June 11-13 in Chicago, spine surgeons, orthopedic leaders and ASC executives will come together to explore minimally invasive techniques, ASC growth strategies and innovations shaping the future of outpatient spine care. Apply for complimentary registration now.

Advertisement

Next Up in Cardiology

Advertisement